Purified anti-human CD85k (ILT3) Antibody

Pricing & Availability
Clone
ZM4.1 (See other available formats)
Other Names
Immunoglobulin-like transcript (ILT) 3, CD85k, Leukocyte Immunoglobulin-Like Receptor subfamily B member 4 (LILRB4), Leukocyte Immunoglobulin-like Receptor 5 (LIR-5)
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
ZM4dot1_Pure_011409.jpg
Human monocyte derived dendritic cells stained with purified ZM4.1 followed by anti-mouse IgG FITC
  • ZM4dot1_Pure_011409.jpg
    Human monocyte derived dendritic cells stained with purified ZM4.1 followed by anti-mouse IgG FITC
Cat # Size Price Quantity Avail. Save
333002 100 µg $110
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Description

CD85k, known as Immunoglobulin-like transcript (ILT) 3, is an inhibitory receptor expressed by dendritic cells and a subset of white blood cells called monocytes.  ILT3, also known as Leukocyte Immunoglobulin-Like Receptor subfamily B member 4 (LILRB4) and Leukocyte Immunoglobulin-like Receptor 5 (LIR-5), is a type I membrane protein that contains cytoplasmic ITIM motifs and is involved in the down-regulation of immune responses. Expression of ILT3 is up-regulated on tolerogenic dendritic cells.

Product Details
Technical data sheet

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
ILT3 fusion protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Product Citations
  1. Zurli V, et al. 2017. Blood. 130:2006. PubMed
RRID
AB_1027638 (BioLegend Cat. No. 333002)

Antigen Details

Structure
Immunoglobulin superfamily
Distribution
Monocytes, Macrophages, and Dendritic Cells
Cell Type
Monocytes, Macrophages, Dendritic cells
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References
1. Cella M, et al. 1997. J. Exp. Med. 185:1743.
2. Penna G, et al. 2005 Blood 5:2044.
Gene ID
11006 View all products for this Gene ID
UniProt
View information about CD85k on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11/30/2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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